MARS Research Study - Individuals with Schizophrenia Spectrum Disorder (SSD)

About this study

Have you been diagnosed with schizophrenia spectrum disorders (SSD)? Anticholinergic Burden (ACB) is the effect of taking multiple medications that block actions in the nervous system. You may be eligible for a research study to examine the impact of ACB reduction and its effects on cognition, functional outcomes, and quality of life.

What you’ll do

Participants will be randomized to one of two groups: ACB reduction group No ACB reduction group In-person study appointments at baseline, 3-months, and 6-months at the University of Pittsburgh. Interviews Questionnaires Blood draws MR Imaging Scans

Who the researchers are looking for

Have you been diagnosed with schizophrenia spectrum disorders (SSD)? Anticholinergic Burden (ACB) is the effect of taking multiple medications that block actions in the nervous system. You may be eligible for a research study to examine the impact of ACB reduction and its effects on cognition, functional outcomes, and quality of life.

Review the provider’s screening questions. These requirements do not guarantee selection.

Time and reward

Advertised reward

Up to $406 · up to $406 and transportation assistance for study visits will be provided

Active participation

Not specified by the provider

Total study duration

6 months

Format & location

In person · Pittsburgh · PA · United States

Source & freshness

Added to our feed

Sep 20, 2026

Source posted

Not supplied

Last checked

Sep 20, 2026