Rapid antidepressant dynamics in acute neuromodulation treatments
In person · Pittsburgh · PA · United States
Research provider: Pitt+Me
About this study
Are you depressed and not receiving treatment? You may be eligible for a research study to look at brain mechanisms that lead to recovery from depression. The study involves multiple functional MRI and neuromodulation sessions. Compensation is provided.
What you’ll do
By participating in this study, you will complete 5 visits. Screening Visit: complete a clinical interview and several questionnaires. Visit 0: complete baseline structural and functional magnetic resonance image (fMRI) scans. Visits 1, 2, and 3: you will receive three sessions of: Transcranial Magnetic Stimulation (TMS) The intravenous administration of a fast-acting or a conventional antidepressant. Functional magnetic resonance image (fMRI) A 1-week follow-up, where you will be asked to report on your mood symptoms after each experimental manipulation.
Who the researchers are looking for
Are you depressed and not receiving treatment? You may be eligible for a research study to look at brain mechanisms that lead to recovery from depression. The study involves multiple functional MRI and neuromodulation sessions. Compensation is provided.
Review the provider’s screening questions. These requirements do not guarantee selection.
Are you an 18-30 year old with a family history of depression? You may be eligible for a research study to examine the structure and function of the brain in young people with and without family histories of mood disorders. Compensation is provided.
Do you often feel down, low, or depressed? You may be eligible for the GATE study, a research study to test a new experimental treatment for depression. Over a 45-day period, participants will complete clinical interviews and questionnaires, receive one infusion of drug or placebo, complete a computer-based training treatment, and complete assessments. Compensation provided.
Are you the birth mother of a baby younger than 4 months? Are you experiencing postpartum depression? You and your baby may be eligible to participate in a research study with the University of Pittsburgh Medical Center on how postpartum mood may influence mother-baby play. Compensation provided.